Two seminars at Center for Mathematical Sciences, August 7, Friday, 14:30 pm - 16:00 pm

时间： August 7, Friday, at 14:30 pm - 16:00 pm

地点： Center for Mathematical Sciences, Room813 (创新研究院恩明楼813室).

报告（一）

报告人： Min Wu (École Normale Supérieure, Paris , France)

标题： Modeling of vascular tumor growth, microenvironmental fluid dynamics and therapy

摘要： Vascularized tumor growth is a complex process spanning a wide range of spatial and temporal scales, and involves inter-related biophysical, chemical and hemodynamic factors in the interplay between tumor formation, vascular remodeling, and angiogenesis. As tumor forms, cells lack of nutrient may begin to secret tumor angiogenesis factors such as vascular endothelial growth factor (VEGF) family members into the surrounding tissues, which remodels local vasculature either by expanding the pre-existing vessels or recruiting new vessels from the pre-existing vascular network (angiogenesis). However,through modifying the fluid flows, tumor-associated structural pathologies compromise the transport of nutrient and therapeutic agents during anti-tumor treatments. In this talk, I will present my theoretical work on elucidating their individual and synergic roles on the tumor microenvironment fluid pressure and associated flows. I will also talk about the drug delivery (e.g., nano-based therapeutic agents) in the tumor microenvironment and the idea of normalization in anti-cancer therapies.

报告（二）

报告人：Zhiwei Wu（宁波大学）

标题： Central affine curve flows and integrable systems

摘要：In this talk, I will talk about evolution of curves in the affine space R^{n}\{0}, the invariants under SL(n) action are solutions of Gelfand-Dickey hierarchy. I will talk about the corresponding Cauchy problem and Backlund transformation for the central affine curve flows. The Hamiltonian formulation will be derived in terms of co-Adjoint orbit.